ChrisR: /* History */

2012-04-13T20:30:57Z

History

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	* On September 27, 2011 23andMe announced at Health 2.0 in San Francisco a limited enrollment pilot program for current members called Exome 80x. The test will measure 50 million base pairs of the participant's [[exome]] at a cost of $999.<ref>{{Cite web\|url=https://www.23andme.com/exome/ \|title=Exome 80x \| publisher= 23andMe \|date=2011-09-27 \|accessdate=2011-09-27 }}</ref> This new test will not be good for ancestry as the test focuses on the exome and will not measure much of mitochondrial or Y-chromosome DNA.		* On September 27, 2011 23andMe announced at Health 2.0 in San Francisco a limited enrollment pilot program for current members called Exome 80x. The test will measure 50 million base pairs of the participant's [[exome]] at a cost of $999.<ref>{{Cite web\|url=https://www.23andme.com/exome/ \|title=Exome 80x \| publisher= 23andMe \|date=2011-09-27 \|accessdate=2011-09-27 }}</ref> This new test will not be good for ancestry as the test focuses on the exome and will not measure much of mitochondrial or Y-chromosome DNA.
	* Technical info November 2011: v3-only raw data download has 960,520 SNPs (1,764 for Y-DNA and 2,459 for mtDNA). Relative Finder looks for segments of DNA from a common ancestor (IBD = Identical By Descent). Segments of at least 7 cM ([[centiMorgan]]s) and at least 700 SNPs are reported. Additional segments need to be at least 5 cM and have at least 700 SNPs.<ref>{{cite web\|title=How does Relative Finder calculate my matches?\|url=https://www.23andme.com/you/faqwin/rfcalculation/\|publisher=23andMe\|accessdate=7 December 2011}}</ref>		* Technical info November 2011: v3-only raw data download has 960,520 SNPs (1,764 for Y-DNA and 2,459 for mtDNA). Relative Finder looks for segments of DNA from a common ancestor (IBD = Identical By Descent). Segments of at least 7 cM ([[centiMorgan]]s) and at least 700 SNPs are reported. Additional segments need to be at least 5 cM and have at least 700 SNPs.<ref>{{cite web\|title=How does Relative Finder calculate my matches?\|url=https://www.23andme.com/you/faqwin/rfcalculation/\|publisher=23andMe\|accessdate=7 December 2011}}</ref>
	* In January 2012 there was a major discussion about the ancestry and genealogical functions of 23andMe. A "Ancestry Ambassador Group" was founded, to canalize user requests. Members are CeCe Moore, Dr. Ann Turner, Larry Vick, Dr. Tim Janzen, Andrea Badger and Shannon Christmas.		* In January 2012 there was a major discussion about the ancestry and genealogical functions of 23andMe. A "Ancestry Ambassador Group" was founded, to canalize user requests. Members are CeCe Moore, Dr. Ann Turner, Larry Vick, Dr. Tim Janzen, Andrea Badger and Shannon Christmas. <ref>http://www.yourgeneticgenealogist.com/2012/01/your-genetic-genealogist-appointed-to.html</ref>
	* On March 31, 2012 23andMe announced the release of the first batch of data to early Exome 80x participants, although many more participants are still awaiting their DNA to be sequenced. <ref>{{cite web\|title=The Spittoon >> Exomes - The First of Many!\|url=http://spittoon.23andme.com/2012/03/31/exomes-the-first-of-many/\|publisher=23andMe\|accessdate=3 April 2012}}</ref>		* On March 31, 2012 23andMe announced the release of the first batch of data to early Exome 80x participants, although many more participants are still awaiting their DNA to be sequenced. <ref>{{cite web\|title=The Spittoon >> Exomes - The First of Many!\|url=http://spittoon.23andme.com/2012/03/31/exomes-the-first-of-many/\|publisher=23andMe\|accessdate=3 April 2012}}</ref>

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2012-04-13T20:22:40Z

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'''23andMe''' Inc. is a privately held personal genomics and biotechnology company based in Mountain View, California<ref>{{Cite web|url=http://www.manta.com/coms2/dnbcompany_6k1rd8 |title=23andMe, Inc. Company Profile |publisher=Manta.com }}</ref> that is providing methods and technologies that will enable consumers to understand their own genetic information. The company is named for the 23 pairs of chromosomes in a normal human cell.

The 23andMe website is split into four categories: Health and Traits, Ancestry, Sharing and Community and Research.

==History==
* 23andMe was founded in April 2006 by Anne Wojcicki and Linda Avey. Esther Dyson is Board Member.
* The initial cost of 23andMe's product for US-consumers in November 2007 was $999 (580,000 [[SNPs]] using Illumina technology).<ref>{{Cite news|url=http://www.usatoday.com/tech/webguide/internetlife/2007-11-20-23andme-launch_N.htm|title=Google-backed 23andMe offers $999 DNA test|accessdate=2011-12-10 | work=USA Today|first=Lisa|last=Baertlein|date=2007-11-20}}</ref>
* In January 2008 the service was extended to Canada and most countries in Europe. In September 2008 the test was updated from V1 to V2 and the cost reduced to $399. This was possible with the Illumina HumanHap550-Quad+ chip, capable to read about 600,000 SNPs (expanded range) from all [[chromosomes]] and the [[mtDNA]].<ref>{{Cite web|url=https://www.23andme.com/about/press/20080909b/ |title=Press Release: 23andMe Democratizes Personal Genetics - September 9, 2008}}</ref>
* In November 2010 23andMe introduced an alternative pricing option of $199 with a required one-year subscription of $5 a month. The newly introduced V3 test reads almost 1,000,000 SNPs with the Illumina OmniExpress Plus customized chip (base OmniExpress 733,202 SNPs). For both ancestral lineages (mitochondrial DNA and Y-DNA) over 2000 SNPs are recorded making possible Haplogroup Discovery of over 750 maternal lineages and over 500 different paternal lineages.<ref>{{Cite web|url=https://www.23andme.com/you/community/thread/10470/ |title=Sale or no Sale - Dr. James M. Owston, December 2, 2011}}; FAQ 23andme: [https://www.23andme.com/you/faqwin/chip/ How does 23andMe genotype my DNA?] [http://daver.info/ysub/errata.htm#versions Y-Chromosome Genome Comparison Errata for 23andME Data Compilation, 5 February 2011]</ref><ref>{{Cite web|url=https://www.23andme.com/ancestry/techniques/ |title=Our Service: Ancestry Features / techniques | publisher= 23andMe |accessdate=2011-12-10 }}</ref>
* In March 2011 the pricing was changed to $99 with $9/month (for at least one year). This subscription would provide subscribers with updates on discoveries made about their DNA over time. A single-fee payment of $399 without the commitment continues also to be available. On the SCGS-Meeting in June 2011 23andMe stated to have tested about 75,000 individuals.<ref>{{Cite web|url=http://www.yourgeneticgenealogist.com/2011/06/news-from-23andme-and-ftdna-at-scgs.html |title=News from 23andMe and FTDNA at SCGS 2011 Jamboree - June 12, 2011}}</ref>
* On June 15, 2011 23andMe announced in three and a half years of service their database has grown to include the DNA data of more than 100,000 people. Other statistics include 60,000 users had completed on average 10 surveys, 100,000 community forum posts, more than 60,000 pairs of relatives have been discovered, 57% of 23andMe users are male, 47% share their data with other users, and 12% have multiple ancestries.<ref>{{Cite web|url=https://www.23andme.com/about/press/23andme_database_100000k_users/ |title=23andMe Database Surpasses 100,000 Users | publisher= 23andMe |accessdate=2012-02-21 }}</ref>
* On September 27, 2011 23andMe announced at Health 2.0 in San Francisco a limited enrollment pilot program for current members called Exome 80x. The test will measure 50 million base pairs of the participant's [[exome]] at a cost of $999.<ref>{{Cite web|url=https://www.23andme.com/exome/ |title=Exome 80x | publisher= 23andMe |date=2011-09-27 |accessdate=2011-09-27 }}</ref> This new test will not be good for ancestry as the test focuses on the exome and will not measure much of mitochondrial or Y-chromosome DNA.
* Technical info November 2011: v3-only raw data download has 960,520 SNPs (1,764 for Y-DNA and 2,459 for mtDNA). Relative Finder looks for segments of DNA from a common ancestor (IBD = Identical By Descent). Segments of at least 7 cM ([[centiMorgan]]s) and at least 700 SNPs are reported. Additional segments need to be at least 5 cM and have at least 700 SNPs.<ref>{{cite web|title=How does Relative Finder calculate my matches?|url=https://www.23andme.com/you/faqwin/rfcalculation/|publisher=23andMe|accessdate=7 December 2011}}</ref>
* In January 2012 there was a major discussion about the ancestry and genealogical functions of 23andMe. A "Ancestry Ambassador Group" was founded, to canalize user requests. Members are CeCe Moore, Dr. Ann Turner, Larry Vick, Dr. Tim Janzen, Andrea Badger and Shannon Christmas.
* On March 31, 2012 23andMe announced the release of the first batch of data to early Exome 80x participants, although many more participants are still awaiting their DNA to be sequenced. <ref>{{cite web|title=The Spittoon >> Exomes - The First of Many!|url=http://spittoon.23andme.com/2012/03/31/exomes-the-first-of-many/|publisher=23andMe|accessdate=3 April 2012}}</ref>

23andMe also provides free testing without subscriptions fees to individuals that qualify for certain research initiatives. Current research initiatives include [[Parkinson's disease]], [[Alzheimer's disease]], [[sarcoma]], [[myeloproliferative neoplasms]], and the Roots into the Future initiative which explores the connection between DNA and disease in [[African Americans]].<ref>{{Cite web|url=https://www.23andme.com/pd/ |title=Parkinson's Disease: Strength in Numbers | publisher= 23andMe |accessdate=2011-09-27 }}</ref><ref>{{Cite web|url=https://www.23andme.com/research/fight_alzheimers/landing/ |title=Help Fight Alzheimer's Disease | publisher= 23andMe |accessdate=2011-09-27 }}</ref><ref>{{Cite web|url=https://www.23andme.com/sarcoma/ |title=23andMe Sarcoma Community: A Patient-Driven Revolution in Sarcoma Research | publisher= 23andMe |accessdate=2011-09-27 }}</ref><ref>{{Cite web|url=https://www.23andme.com/mpn/ |title=23andMe Myeloproliferative Neoplasms Research Initiative | publisher= 23andMe |accessdate=2011-09-27 }}</ref><ref>{{Cite web|url=https://www.23andme.com/roots/ |title=Roots into the Future | publisher= 23andMe |accessdate=2011-09-27 }}</ref> On March 20, 2012 23andMe announced a new free research initiative for qualifying people with [[Metastatic Breast Cancer]].<ref>{{Cite web|url=https://www.23andme.com/invite-study/ |title=InVite Study in Metastatic Breast Cancer | publisher= 23andMe |accessdate=2012-03-20 }}</ref>

Both [[Google]] and [[New Enterprise Associates]] have invested in 23andMe. Google has invested $3.9M and recently another $2.6M in 23andMe, whose co-founder [[Anne Wojcicki]] is married to Google co-founder [[Sergey Brin]].<ref>{{Cite news|title=Google invests in genetics firm |url=http://news.bbc.co.uk/2/hi/business/6682451.stm |publisher=[[BBC]] News |date=2007-05-22 |accessdate=2007-06-28 }}</ref> [[Genentech]] is also reported to have invested in 23andMe.<ref name=GigaOM>{{Cite web|url=http://gigaom.com/2007/05/24/google-sergey-and-23andme-why-it-all-makes-sense/ |title=Google, Sergey and 23andMe: Why it all makes sense |author=Kevin Kelleher |publisher=GigaOmniMedia |date=2007-05-24 |accessdate=2007-06-27 | archiveurl= http://web.archive.org/web/20070626184305/http://gigaom.com/2007/05/24/google-sergey-and-23andme-why-it-all-makes-sense/| archivedate= 26 June 2007 | deadurl= no}}</ref>

==See also==
*[[DNA Testing Companies Overview]]
*[[FTDNA]]

==References==
<references />

==External links==
*[https://www.23andme.com/ Official 23andMe Website]
*[http://spittoon.23andme.com/ Official 23andMe Blog]
*[https://www.youtube.com/user/23andMe Official 23andMe YouTube Channel]
*[http://venturebeat.com/2007/01/18/roundup-genetics-semels-choke-wikiseek-myspace-story-and-more/ Venture Beat Story]
*[http://www.thegeneticgenealogist.com/2007/04/09/23andme-revisited/ Mention in "The Genetic Genealogist"]
*[http://www.wired.com/medtech/genetics/magazine/15-12/ff_genomics Wired Magazine article November 2007]
*[http://www.crunchbase.com/company/23andme CrunchBase Company Profile]
*[http://www.socialnetworkingwatch.com/2009/10/chia-hwu-community-manager-at-23andmecom.html Community Manager Chia Hwu Interview, Social Networking Watch, October 2009]
*[http://www.cyberpunkreview.com/news-as-cyberpunk/wired-magazine-issue-1512-welcome-to-the-age-of-genomics/ "Genomics" article]

[[Kategorie:Genetic Genealogy]]
[[Kategorie:English]]

23andMe - Versionsgeschichte

ChrisR: /* History */

ChrisR: Die Seite wurde neu angelegt: „'''23andMe''' Inc. is a privately held personal genomics and biotechnology company based in Mountain View, California{{Cite web|url=http://www.manta.com/c…“